Exploring common and rare diseases genetics with GWAS and NGS
Lausanne, 16-19 March 2015
Participants will learn about the genome-wide analysis of variation including GWAS, next generation sequencing (NGS) and how to identify and interpret variants in exomes. The course will also introduce techniques to extend GWAS using NGS data.
After four days of lectures and practical exercises, participants should have a clear understanding of genome variation, how to perform GWAS and exome analyses, and how to apply these techniques in translational research.
Skill requirements: Participants should have a good understanding of command-line UNIX (UNIX Fundamentals self-learning module) in order to perform the practical exercises.
Material requirements: A WiFi-equipped laptop with 3-4GB of RAM, 60GB free hard-disk space You will be given virtual machine images with all softwares and packages needed for this course.
Application is now closed.
Deadline for registration and cancellation is set to the 6th of March 2015.
Genopode Building. classroom is 2020, except Monday morning, which is Auditorium A.
Please also note that you need a computer with minimum of 4 GB memory. The virtual machine itself requires 2 GB memory. And at least 10 GB free space on your hard disk.
AM Aurélien Macé (Statistical Genetics group (IUMSP/CHUV/UNIL/SIB)
BS Brian Stevenson (Vital-IT group (SIB)
SP Sylvain Pradervand (LGTF/Vital-IT (UNIL/SIB))
SR Sina Rüeger (Statistical Genetics group (IUMSP/CHUV/UNIL/SIB)
ZK Zoltán Kutalik (Statistical Genetics group (IUMSP/CHUV/UNIL)
09:00 – 11:00 GWAS - basics (ZK)
11:30 – 12:00 GWAS - advanced (ZK)
12:00 – 14:00 “Social lunch”
14:00 – 17:00 Practical (ZK)
GWAS - Basics (slides)
GWAS - Advanced (slides)
09:00 – 12:00 Exome Sequencing: From DNA sample to variants file (SP)
13:30 – 17:00 Practical (SP + BS)
Exome Sequencing: From DNA sample to variants file
09:00 – 10:30 Variant annotation and prioritization (part 1) (BS)
11:00 – 12:30 Variant annotation and prioritization (part 2) (BS)
14:00 – 17:00 Practical (BS + SP)