This two-days course will present the statistical analysis of differential gene expression based on techniques such as microarrays, RNA-seq and qPCR. Lectures will be conducted in the morning, and students will analyze actual gene expression data in the afternoon. The first day will cover microarray analysis and validation with qPCR. The second day will cover RNAseq analysis and downstream analysis (e.g. GO analysis). The course is organized jointly by the Bioinformatics Core Facility in Lausanne and the BUGFri core facility in Fribourg.