Topic outline

  • Enrichment analysis

    Lausanne, 11 March 2019

    University of Lausanne, Amphipôle building, room 202

    This page is addressed to registered participants. To access course description and application form, please click here.

    For any assistance, please contact training@sib.swiss.

    • R packages to install PRIOR TO the course

      library("clusterProfiler") 
      library("AnnotationDbi")
      library("rat2302.db")
      library(“DescTools”)
      library(org.Hs.eg.db)
      library(org.Rn.eg.db)

      • Schedule

        9:00  - 10:30    

        Recall:

        a. Differential expression

        b. Statistical tests

        Exercise

        10:30  - 10:45    coffee break

        10:45  - 12:30    

        Threshold-based versus Threshold-free enrichment

        GSEA advantages and drawbacks

        Classification of available gene enrichment methods

        Exercise

        12:30  - 13:30  lunch (on your own)

        13:30  - 15:30   

        Generalizing enrichment

        Exercice

        15:30  - 15:45  coffee break

        15:45  - 17:00  

        Ontologies and enrichment

        Exercise

        17:00    end of day