Section outline

  • Wednesday 31 August 2016

    09:00 - 10:30

    Hybrid Models of Metabolic Networks
    Jörg Stelling (Computational Systems Biology Group, SIB & ETH Zurich D-BSSE, Basel)

    Details:
    1. FBA and its variants: Mathematical foundations, linear and non-linear optimization
    2. Incorporating experimental data: metabolic flux analysis, integration of -omics data
    3. Toward hybrid models: regulatory logig, dynamic FBA
    10:30 - 11:00 Coffee break
    11:00 – 12:30 Continued
    12:30 – 14:00 Lunch
    14:00 - 17:00

    Mini-Symposium

    14:00 - 14:40
    A hierarchy of decisions that impact the accuracy of tissue-specific metabolic models.
    Prof. Nathan E. Lewis
    Systems biochemistry and cell engineering lab, University of California, San Diego

    14:40 - 15:20
    Automated generation of realistic models.
    Prof. Dr. Jörg Stelling
    Computational Systems Biology Group, SIB & ETH Zurich D-BSSE, Basel

    15:20 - 15:40
    Break

    15:40 - 16:20
    Towards a more accurate prediction of the biotransformation of chemical contaminants - What can we learn from combining data mining, analytical chemistry and biology tools?
    Dr. Kathrin Fenner
    Department Environmental Chemistry, EAWAG, Dübendorf

    16:20 - 17:00
    Gene Ontology: biases, pitfalls, remedies.
    Prof. Christophe Dessimoz,
    Computational Evolutionary Biology and Genomics, SIB & Department of Ecology and Evolution, University of Lausanne