cancer cell linecell line established from a tumor tissue; the most widely used reagent in laboratory-based cancer research to study the biology of cancer and to test cancer treatments |
controlled vocabularya standardized terminology for use in indexing and retrieval of information |
embryonic stem cells (ES cells or ESCs)pluripotent stem cells generated from the inner cell mass of a blastocyst, an early-stage pre-implantation embryo; ESCs are being studied to be used as clinical therapies, models of genetic disorders, and cellular/DNA repair |
finite cell linecell line that can undergo a finite number of divisions |
hybridomahybrid cell line that results from the fusion of B cells and myeloma cells; hybridomas are immortalized cells which produce antibodies |
immortalized cell linecell line that can divide indefinitely |
induced pluripotent stem cells (iPSCs)cells derived from skin or blood cells that have been reprogrammed back into an embryonic-like pluripotent state, thus enabling the development of an unlimited source of any type of human cell needed for therapeutic purposes |
pluripotent cellcell capable of giving rise to several different cell types |
primary cellscells taken directly from the tissue and processed to establish them under optimized culture for a limited number of divisions; they most closely represent the tissue of origin conditions |
short tandem repeat (STR)short sequences of DNA (2–6 bp) that are repeated numerous times in a head-tail manner; the number of repeat units is highly variable among individuals, hence STRs are used for identification and authentication purposes |