The goal of this one-day workshop is to give some basic theoretical and practical knowledge on protein sequence databases and, in particular, on the optimum use of the UniProt web site:

• Where do the protein sequences come from?
• What are the differences between UniProtKB/TrEMBL and UniProtKB/Swiss-Prot?
• What the manual and automated annotation pipelines ?
• How to estimate the protein sequence accuracy and the annotation quality?
• How to retrieve large dataset (i.e. complete proteome) for a particular organism?
• How to extract biological knowledge from a Blast result?
• What are the differences between UniProt and the NCBI protein sequence databases?
• How to retrieve accession numbers or GIs or other record identifiers corresponding to the proteins of interest?